Applied cefotaxime for infections halotestin buy caused by microorganisms sensitive to it (mainly Gram): infections of the respiratory and urinary tract infections, kidney; ear infections, throat, nose, septicemia, endocarditis, meningitis; infections of the bones and soft tissues of the abdominal cavity; in infectious and inflammatory diseases of the pelvic organs, gonorrhea; wound and burn infections and others.
Dosage and administration
Apply cefotaxime intramuscularly and intravenously. For intramuscular injection, or dissolved 0.25 g in 0.5 mL 2 (respectively 1 g in 4 ml) of sterile water for injection, injected deep into the gluteal muscle. As the solvent, when administered intramuscularly also used 1% lidocaine (0.5 g – 2 mL per 1 g – 4 ml).
For intravenous cefotaxime 0.5-1 g dissolved in 4 mL (2 g – 10 ml) sterile water for injection. Enter slowly for 3-5 minutes.
For a drip (for 50-60 minutes) was dissolved 2 g in 100 ml of isotonic sodium chloride solution or 5% glucose solution.
The usual dose of cefotaxime for adults and children over 12 years – 1 g every 12 hours. In severe cases, the dose was increased to 3 or 4 grams per halotestin buy day, the drug is administered 3 or 4 times, the 1 maximum daily dose, depending on the severity of the disease, can be increased to 12, the
usual dosage for infants and children younger than 12 years – 50 -100 mg / kg of body weight per day of administration at intervals of 6 to 12 hours. For premature infants the daily dose should not exceed 50 mg / kg.
In the case of renal impairment, reduce the dose. If creatinine clearance of 10 ml / min or less daily dose halved.
The drug is contraindicated in case of hypersensitivity to cephalosporin antibiotics. Possible cross-allergy between penicillins and cephalosporins.
Caution is needed when administering the drug to patients with impaired renal and hepatic function.
In children up to 2.5 years old can not use the intramuscular administration of the drug.
Pregnancy and lactation
Use of the drug during pregnancy is possible only when the intended benefits to the mother outweighs the potential risk to the fetus.
Cefotaxime is excreted in breast milk, so breast-feeding should be discontinued, if necessary, the appointment during lactation.
Before the appointment of the drug should be collected allergic history, especially with regard to beta-lactam antibiotics. Known cross-allergy between penicillins and cephalosporins. In persons with a history there are indications of an allergic reaction to penicillin, the drug is used with extreme caution.
In the event of hypersensitivity reactions (which are severe and even lead to death) drug overturned.
When the duration of drug treatment over 10 days need to be monitored picture peripheral blood.
Maybe detect false positive halotestin buy test.
When the determination of glucose in the urine of non-enzymatic method (for example, by Benedict) may be false-positive results.
Interaction with other drugs
With simultaneous use of cefotaxime with potentially nephrotoxic drugs (aminoglycosides, furosemide) need to monitor renal function (risk of nephrotoxicity of the latter).
Solutions of cefotaxime incompatible with solutions of other antibiotics in the same syringe or dropper.
When using cefotaxime, allergic reactions (skin rash, fever, anaphylactic shock), indigestion (dyspepsia, pseudomembranous colitis (rarely), violations of liver function tests), increase in the number of eosinophils, leukopenia, neutropenia, agranulocytosis, hemolytic anemia, increased alkaline phosphatase and azotomocheviny content in urine. Pain, redness and swelling at the site of injection. Can increase the body temperature.
Powder for solution for halotestin buy injection.
At 250 mg, 500 mg or 1 g of cefotaxime in a vial of clear, colorless, neutral glass (class I), a sealed rubber stopper under an aluminum run and closed at the top protective plastic cover.
1 bottle with instructions for use placed in a cardboard box.